| 1 | How the Grinch Stole Christmas (2000) (Universal) | $440,965,000 | $93,405,000 | $31,135,000 | Nov 17, 2000 |
| 2 | Cast Away (Fox) | $396,178,000 | $48,981,000 | $16,327,000 | Dec 22, 2000 |
| 3 | Mission: Impossible II (Paramount) | $365,277,000 | $98,091,000 | $32,697,000 | May 24, 2000 |
| 4 | Gladiator (2000) (DreamWorks) | $318,298,000 | $59,044,000 | $19,681,000 | May 05, 2000 |
| 5 | What Women Want (2000) (Paramount) | $310,000,000 | $57,001,000 | $19,000,000 | Dec 15, 2000 |
| 6 | The Perfect Storm (Warner Bros.) | $309,672,000 | $70,080,000 | $23,360,000 | Jun 30, 2000 |
| 7 | Meet the Parents (Universal) | $281,907,000 | $48,536,000 | $16,179,000 | Oct 06, 2000 |
| 8 | X-Men (Fox) | $266,738,000 | $92,370,000 | $30,790,000 | Jul 14, 2000 |
| 9 | Scary Movie (Miramax / Dimension) | $266,263,000 | $71,809,000 | $23,936,000 | Jul 07, 2000 |
| 10 | What Lies Beneath (DreamWorks) | $263,619,000 | $50,369,000 | $16,790,000 | Jul 21, 2000 |
| 11 | Dinosaur (Disney) | $233,585,000 | $65,887,000 | $21,962,000 | May 19, 2000 |
| 12 | Crouching Tiger, Hidden Dragon (Sony Pictures Classics) | $217,187,000 | $1,123,000 | $374,000 | Dec 08, 2000 |
| 13 | Erin Brockovich (Universal) | $212,976,000 | $47,716,000 | $15,905,000 | Mar 17, 2000 |
| 14 | Charlie's Angels (2000) (Sony / Columbia) | $212,484,000 | $68,049,000 | $22,683,000 | Nov 03, 2000 |
| 15 | Traffic (USA Films) | $210,467,000 | $26,316,000 | $8,772,000 | Dec 27, 2000 |
| 16 | Nutty Professor II: The Klumps (Universal) | $209,100,000 | $72,099,000 | $24,033,000 | Jul 28, 2000 |
| 17 | Big Momma's House (Fox) | $199,349,000 | $43,512,000 | $14,504,000 | Jun 02, 2000 |
| 18 | Remember the Titans (Disney) | $196,118,000 | $35,451,000 | $11,817,000 | Sep 29, 2000 |
| 19 | The Patriot (Sony / Columbia) | $192,178,000 | $38,009,000 | $12,670,000 | Jun 28, 2000 |
| 20 | Chicken Run (DreamWorks) | $181,162,000 | $29,686,000 | $9,895,000 | Jun 21, 2000 |
| 21 | Miss Congeniality (Warner Bros.) | $181,116,000 | $23,492,000 | $7,831,000 | Dec 22, 2000 |
| 22 | Gone in 60 Seconds (Disney) | $172,368,000 | $42,962,000 | $14,321,000 | Jun 09, 2000 |
| 23 | Unbreakable (Disney) | $161,113,000 | $51,435,000 | $17,145,000 | Nov 22, 2000 |
| 24 | Me, Myself & Irene (Fox) | $153,583,000 | $41,053,000 | $13,684,000 | Jun 23, 2000 |
| 25 | Space Cowboys (Warner Bros.) | $153,404,000 | $30,682,000 | $10,227,000 | Aug 04, 2000 |
| 26 | The Emperor's New Groove (Disney) | $151,433,000 | $16,639,000 | $5,546,000 | Dec 15, 2000 |
| 27 | Scream 3 (Miramax / Dimension) | $151,164,000 | $58,865,000 | $19,622,000 | Feb 04, 2000 |
| 28 | U-571 (Universal) | $130,779,000 | $33,158,000 | $11,053,000 | Apr 21, 2000 |
| 29 | Rugrats in Paris: The Movie (Paramount) | $129,736,000 | $38,524,000 | $12,841,000 | Nov 17, 2000 |
| 30 | The Family Man (Universal) | $128,525,000 | $25,612,000 | $8,537,000 | Dec 22, 2000 |
| 31 | Hollow Man (Sony / Columbia) | $124,144,000 | $44,792,000 | $14,931,000 | Aug 04, 2000 |
| 32 | Chocolat (2000) (Miramax) | $121,260,000 | $267,000 | $89,000 | Dec 15, 2000 |
| 33 | Shaft (2000) (Paramount) | $119,269,000 | $36,822,000 | $12,274,000 | Jun 16, 2000 |
| 34 | Disney's The Kid (Disney) | $118,179,000 | $21,515,000 | $7,172,000 | Jul 07, 2000 |
| 35 | Vertical Limit (Sony / Columbia) | $117,418,000 | $26,297,000 | $8,766,000 | Dec 08, 2000 |
| 36 | Road Trip (DreamWorks) | $116,226,000 | $26,258,000 | $8,753,000 | May 19, 2000 |
| 37 | Bring It On (Universal) | $115,953,000 | $29,439,000 | $9,813,000 | Aug 25, 2000 |
| 38 | 102 Dalmatians (Disney) | $113,543,000 | $33,719,000 | $11,240,000 | Nov 22, 2000 |
| 39 | Rules of Engagement (Paramount) | $104,009,000 | $25,455,000 | $8,485,000 | Apr 07, 2000 |
| 40 | The Cell (New Line) | $104,006,000 | $29,701,000 | $9,900,000 | Aug 18, 2000 |
| 41 | Mission to Mars (Disney) | $103,241,000 | $38,756,000 | $12,919,000 | Mar 10, 2000 |
| 42 | Coyote Ugly (Disney) | $103,077,000 | $29,369,000 | $9,790,000 | Aug 04, 2000 |
| 43 | Fantasia 2000 (Disney) | $102,856,000 | $3,884,000 | $1,295,000 | Jan 01, 2000 |
| 44 | Snow Day (Paramount) | $101,778,000 | $24,303,000 | $8,101,000 | Feb 11, 2000 |
| 45 | Next Friday (New Line) | $97,214,000 | $24,573,000 | $8,191,000 | Jan 12, 2000 |
| 46 | The Whole Nine Yards (Warner Bros.) | $97,101,000 | $23,286,000 | $7,762,000 | Feb 18, 2000 |
| 47 | Shanghai Noon (Disney) | $96,551,000 | $26,465,000 | $8,822,000 | May 26, 2000 |
| 48 | Romeo Must Die (Warner Bros.) | $94,917,000 | $30,548,000 | $10,183,000 | Mar 22, 2000 |
| 49 | Final Destination (New Line) | $90,437,000 | $16,984,000 | $5,661,000 | Mar 17, 2000 |
| 50 | Finding Forrester (Sony / Columbia) | $87,846,000 | $1,189,000 | $396,000 | Dec 22, 2000 |
| 51 | The Road to El Dorado (DreamWorks) | $86,250,000 | $21,784,000 | $7,261,000 | Mar 31, 2000 |
| 52 | Men of Honor (Fox) | $82,783,000 | $22,620,000 | $7,540,000 | Nov 10, 2000 |
| 53 | Dude, Where's My Car? (Fox) | $79,240,000 | $23,479,000 | $7,826,000 | Dec 15, 2000 |
| 54 | The Tigger Movie (Disney) | $77,248,000 | $15,985,000 | $5,328,000 | Feb 11, 2000 |
| 55 | O Brother, Where Art Thou? (Disney) | $77,178,000 | $331,000 | $110,000 | Dec 22, 2000 |
| 56 | Frequency (New Line) | $76,325,000 | $15,305,000 | $5,102,000 | Apr 28, 2000 |
| 57 | The Replacements (Warner Bros.) | $75,863,000 | $18,720,000 | $6,240,000 | Aug 11, 2000 |
| 58 | Pokemon: The Movie 2000 (Warner Bros.) | $74,203,000 | $33,195,000 | $11,065,000 | Jul 21, 2000 |
| 59 | The Beach (Fox) | $67,466,000 | $25,907,000 | $8,636,000 | Feb 11, 2000 |
| 60 | The Exorcist: The Version You've Never Seen (Warner Bros.) | $67,273,000 | $13,864,000 | $4,621,000 | Sep 22, 2000 |
| 61 | Little Nicky (New Line) | $66,922,000 | $27,240,000 | $9,080,000 | Nov 10, 2000 |
| 62 | Pitch Black (USA Films) | $66,541,000 | $19,728,000 | $6,576,000 | Feb 18, 2000 |
| 63 | The Original Kings of Comedy (Paramount) | $64,747,000 | $18,744,000 | $6,248,000 | Aug 18, 2000 |
| 64 | Bedazzled (2000) (Fox) | $64,246,000 | $22,225,000 | $7,408,000 | Oct 20, 2000 |
| 65 | Autumn in New York (MGM) | $64,034,000 | $18,631,000 | $6,210,000 | Aug 11, 2000 |
| 66 | 28 Days (Sony / Columbia) | $63,031,000 | $17,484,000 | $5,828,000 | Apr 14, 2000 |
| 67 | Keeping the Faith (Disney) | $62,822,000 | $13,699,000 | $4,566,000 | Apr 14, 2000 |
| 68 | Bounce (Miramax) | $62,412,000 | $19,372,000 | $6,457,000 | Nov 17, 2000 |
| 69 | Hanging Up (Sony / Columbia) | $61,131,000 | $26,641,000 | $8,880,000 | Feb 18, 2000 |
| 70 | The Flintstones in Viva Rock Vegas (Universal) | $59,807,000 | $17,836,000 | $5,945,000 | Apr 28, 2000 |
| 71 | The Skulls (Universal) | $59,429,000 | $18,716,000 | $6,239,000 | Mar 31, 2000 |
| 72 | The 6th Day (Sony / Columbia) | $58,680,000 | $22,081,000 | $7,360,000 | Nov 17, 2000 |
| 73 | Thirteen Days (New Line) | $58,660,000 | $16,565,000 | $5,522,000 | Dec 25, 2000 |
| 74 | My Dog Skip (Warner Bros.) | $57,883,000 | $97,000 | $32,000 | Jan 14, 2000 |
| 75 | Where the Heart Is (Fox) | $57,268,000 | $14,063,000 | $4,688,000 | Apr 28, 2000 |
| 76 | Pay It Forward (Warner Bros.) | $56,839,000 | $16,332,000 | $5,444,000 | Oct 20, 2000 |
| 77 | Dracula 2000 (Miramax / Dimension) | $55,997,000 | $14,645,000 | $4,882,000 | Dec 22, 2000 |
| 78 | Return to Me (MGM) | $55,488,000 | $13,262,000 | $4,421,000 | Apr 07, 2000 |
| 79 | Proof of Life (Warner Bros.) | $55,278,000 | $17,310,000 | $5,770,000 | Dec 08, 2000 |
| 80 | Almost Famous (DreamWorks) | $55,170,000 | $3,925,000 | $1,308,000 | Sep 15, 2000 |
| 81 | The Legend of Bagger Vance (DreamWorks) | $52,432,000 | $19,529,000 | $6,510,000 | Nov 03, 2000 |
| 82 | Snatch (Sony / Screen Gems) | $51,429,000 | $47,000 | $16,000 | Dec 08, 2000 |
| 83 | The Art of War (Warner Bros.) | $51,226,000 | $17,654,000 | $5,885,000 | Aug 25, 2000 |
| 84 | Bless the Child (Paramount) | $49,822,000 | $15,963,000 | $5,321,000 | Aug 11, 2000 |
| 85 | The Watcher (Universal) | $49,086,000 | $15,369,000 | $5,123,000 | Sep 08, 2000 |
| 86 | Love & Basketball (New Line) | $46,565,000 | $13,802,000 | $4,601,000 | Apr 21, 2000 |
| 87 | High Fidelity (Disney) | $46,272,000 | $10,902,000 | $3,634,000 | Mar 31, 2000 |
| 88 | Book of Shadows: Blair Witch 2 (Artisan) | $44,830,000 | $22,424,000 | $7,475,000 | Oct 27, 2000 |
| 89 | The Adventures of Rocky & Bullwinkle (Universal) | $44,098,000 | $11,555,000 | $3,852,000 | Jun 30, 2000 |
| 90 | Nurse Betty (USA Films) | $42,683,000 | $12,118,000 | $4,039,000 | Sep 08, 2000 |
| 91 | Reindeer Games (Miramax / Dimension) | $39,627,000 | $13,784,000 | $4,595,000 | Feb 25, 2000 |
| 92 | Titan A.E. (Fox) | $38,584,000 | $15,901,000 | $5,300,000 | Jun 16, 2000 |
| 93 | Billy Elliot (Universal Focus) | $37,298,000 | $366,000 | $122,000 | Oct 13, 2000 |
| 94 | Boys and Girls (Miramax / Dimension) | $36,967,000 | $11,885,000 | $3,962,000 | Jun 16, 2000 |
| 95 | Battlefield Earth (Warner Bros.) | $36,410,000 | $19,584,000 | $6,528,000 | May 12, 2000 |
| 96 | Urban Legends: Final Cut (Sony / Columbia) | $36,405,000 | $14,423,000 | $4,808,000 | Sep 22, 2000 |
| 97 | Down to You (Miramax) | $34,033,000 | $12,892,000 | $4,297,000 | Jan 21, 2000 |
| 98 | Wonder Boys (Paramount) | $32,886,000 | $9,850,000 | $3,283,000 | Feb 23, 2000 |
| 99 | Best in Show (Warner Bros.) | $31,737,000 | $701,000 | $234,000 | Sep 29, 2000 |
| 100 | The Ninth Gate (Artisan) | $31,645,000 | $11,230,000 | $3,743,000 | Mar 10, 2000 |
| 101 | Michael Jordan to the Max (IMAX) | $31,627,000 | $980,000 | $327,000 | May 05, 2000 |
| 102 | The Contender (DreamWorks) | $30,307,000 | $9,096,000 | $3,032,000 | Oct 13, 2000 |
| 103 | Red Planet (Warner Bros.) | $29,643,000 | $14,789,000 | $4,930,000 | Nov 10, 2000 |
| 104 | Small Time Crooks (DreamWorks) | $29,280,000 | $6,581,000 | $2,194,000 | May 19, 2000 |
| 105 | Center Stage (Sony / Columbia) | $29,167,000 | $7,808,000 | $2,603,000 | May 12, 2000 |
| 106 | Boiler Room (New Line) | $28,778,000 | $11,400,000 | $3,800,000 | Feb 18, 2000 |
| 107 | Lost Souls (New Line) | $28,514,000 | $13,489,000 | $4,496,000 | Oct 13, 2000 |
| 108 | Eye of the Beholder (Destination) | $27,981,000 | $10,106,000 | $3,369,000 | Jan 28, 2000 |
| 109 | Thomas and the Magic Railroad (Destination) | $27,020,000 | $7,046,000 | $2,349,000 | Jul 26, 2000 |
| 110 | Cirque du Soleil: Journey of Man (Sony Pictures Classics) | $26,500,000 | $85,000 | $28,000 | May 05, 2000 |
| 111 | Loser (Sony / Columbia) | $26,484,000 | $10,189,000 | $3,396,000 | Jul 21, 2000 |
| 112 | All the Pretty Horses (Miramax) | $26,352,000 | $8,242,000 | $2,747,000 | Dec 25, 2000 |
| 113 | Drowning Mona (Destination) | $26,295,000 | $9,839,000 | $3,280,000 | Mar 03, 2000 |
| 114 | Bait (Warner Bros.) | $25,988,000 | $9,302,000 | $3,101,000 | Sep 15, 2000 |
| 115 | Dungeons & Dragons (2000) (New Line) | $25,810,000 | $12,273,000 | $4,091,000 | Dec 08, 2000 |
| 116 | American Psycho (Lionsgate) | $25,556,000 | $8,413,000 | $2,804,000 | Apr 14, 2000 |
| 117 | The Next Best Thing (Paramount) | $25,419,000 | $9,955,000 | $3,318,000 | Mar 03, 2000 |
| 118 | Get Carter (Warner Bros.) | $25,380,000 | $11,256,000 | $3,752,000 | Oct 06, 2000 |
| 119 | Supernova (MGM) | $24,131,000 | $11,416,000 | $3,805,000 | Jan 14, 2000 |
| 120 | The Ladies Man (Paramount) | $23,090,000 | $9,202,000 | $3,067,000 | Oct 13, 2000 |
| 121 | The Little Vampire (New Line) | $23,016,000 | $9,699,000 | $3,233,000 | Oct 27, 2000 |
| 122 | Dr. T and the Women (Artisan) | $22,238,000 | $8,500,000 | $2,833,000 | Oct 12, 2000 |
| 123 | The Crew (Disney) | $22,084,000 | $6,871,000 | $2,290,000 | Aug 25, 2000 |
| 124 | Highlander: Endgame (Miramax / Dimension) | $21,725,000 | $10,553,000 | $3,518,000 | Sep 01, 2000 |
| 125 | Ready to Rumble (Warner Bros.) | $21,018,000 | $8,916,000 | $2,972,000 | Apr 07, 2000 |
| 126 | Saving Grace (Fine Line) | $20,652,000 | $487,000 | $162,000 | Aug 04, 2000 |
| 127 | The Gift (2000) (Paramount Classics) | $20,364,000 | $20,000 | $7,000 | Dec 22, 2000 |
| 128 | The Legend of Drunken Master (Miramax / Dimension) | $19,595,000 | $6,521,000 | $2,174,000 | Oct 20, 2000 |
| 129 | Cyberworld 3-D (IMAX) | $19,083,000 | $472,000 | $157,000 | Oct 06, 2000 |
| 130 | Here on Earth (Fox) | $17,843,000 | $7,649,000 | $2,550,000 | Mar 15, 2000 |
| 131 | Lucky Numbers (Paramount) | $17,029,000 | $7,693,000 | $2,564,000 | Oct 27, 2000 |
| 132 | Godzilla 2000 (Sony / TriStar) | $17,021,000 | $7,474,000 | $2,491,000 | Aug 18, 2000 |
| 133 | 3 Strikes (MGM) | $16,673,000 | $6,248,000 | $2,083,000 | Mar 03, 2000 |
| 134 | Digimon: The Movie (Fox) | $16,332,000 | $7,179,000 | $2,393,000 | Oct 06, 2000 |
| 135 | You Can Count on Me (Paramount Classics) | $15,573,000 | $200,000 | $67,000 | Nov 10, 2000 |
| 136 | Whatever It Takes (Sony / Columbia) | $14,831,000 | $6,960,000 | $2,320,000 | Mar 24, 2000 |
| 137 | Pollock (Sony Pictures Classics) | $14,580,000 | $75,000 | $25,000 | Dec 15, 2000 |
| 138 | Shadow of the Vampire (Lionsgate) | $14,063,000 | $255,000 | $85,000 | Dec 29, 2000 |
| 139 | Quills (Fox Searchlight) | $11,981,000 | $423,000 | $141,000 | Nov 24, 2000 |
| 140 | Screwed (Universal) | $11,917,000 | $5,665,000 | $1,888,000 | May 12, 2000 |
| 141 | State and Main (Fine Line) | $11,776,000 | $984,000 | $328,000 | Dec 22, 2000 |
| 142 | I Dreamed of Africa (Sony / Columbia) | $11,278,000 | $4,089,000 | $1,363,000 | May 05, 2000 |
| 143 | What Planet Are You From? (Sony / Columbia) | $10,669,000 | $5,102,000 | $1,701,000 | Mar 03, 2000 |
| 144 | Croupier (Shooting Gallery) | $10,516,000 | $108,000 | $36,000 | Apr 21, 2000 |
| 145 | The Way of the Gun (Artisan) | $10,269,000 | $3,647,000 | $1,216,000 | Sep 08, 2000 |
| 146 | Where the Money Is (USA Films) | $9,600,000 | $4,262,000 | $1,421,000 | Apr 14, 2000 |
| 147 | The In Crowd (Warner Bros.) | $8,955,000 | $2,553,000 | $851,000 | Jul 21, 2000 |
| 148 | Black and White (Sony / Columbia) | $8,949,000 | $3,752,000 | $1,251,000 | Apr 07, 2000 |
| 149 | Gossip (Warner Bros.) | $8,662,000 | $3,937,000 | $1,312,000 | Apr 21, 2000 |
| 150 | Woman on Top (Fox Searchlight) | $8,513,000 | $3,405,000 | $1,135,000 | Sep 22, 2000 |
| 151 | The Virgin Suicides (Paramount Classics) | $8,320,000 | $399,000 | $133,000 | Apr 21, 2000 |
| 152 | Duets (Disney) | $8,037,000 | $3,396,000 | $1,132,000 | Sep 15, 2000 |
| 153 | Held Up (Trimark) | $7,980,000 | $3,241,000 | $1,080,000 | May 12, 2000 |
| 154 | The Tao of Steve (Sony Classics) | $7,364,000 | $156,000 | $52,000 | Aug 04, 2000 |
| 155 | Before Night Falls (Fine Line) | $7,193,000 | $145,000 | $48,000 | Dec 22, 2000 |
| 156 | Dancer in the Dark (Fine Line) | $7,097,000 | $155,000 | $52,000 | Sep 22, 2000 |
| 157 | East is East (Miramax) | $7,083,000 | $91,000 | $30,000 | Apr 14, 2000 |
| 158 | Whipped (Destination) | $7,053,000 | $4,629,000 | $1,543,000 | Sep 01, 2000 |
| 159 | Requiem for a Dream (Artisan) | $6,165,000 | $110,000 | $37,000 | Oct 06, 2000 |
| 160 | The Big Blue: Director's Cut (2000) (IDP) | $6,072,000 | $24,000 | $8,000 | Jul 14, 2000 |
| 161 | Malèna (Miramax) | $5,847,000 | $106,000 | $35,000 | Dec 22, 2000 |
| 162 | Price of Glory (New Line) | $5,835,000 | $2,733,000 | $911,000 | Mar 31, 2000 |
| 163 | Ghost Dog: The Way of the Samurai (Artisan) | $5,610,000 | $282,000 | $94,000 | Mar 03, 2000 |
| 164 | The Big Kahuna (Lions Gate) | $5,368,000 | $137,000 | $46,000 | Apr 28, 2000 |
| 165 | Beautiful (Destination) | $5,355,000 | $2,390,000 | $797,000 | Sep 29, 2000 |
| 166 | The House of Mirth (Sony Classics) | $5,162,000 | $83,000 | $28,000 | Dec 22, 2000 |
| 167 | Isn't She Great (Universal) | $5,024,000 | $2,319,000 | $773,000 | Jan 28, 2000 |
