| 1 | How the Grinch Stole Christmas (2000) (Universal) | $447,237,000 | $94,734,000 | $31,578,000 | Nov 17, 2000 |
| 2 | Cast Away (Fox) | $401,813,000 | $49,677,000 | $16,559,000 | Dec 22, 2000 |
| 3 | Mission: Impossible II (Paramount) | $370,472,000 | $99,486,000 | $33,162,000 | May 24, 2000 |
| 4 | Gladiator (2000) (DreamWorks) | $322,826,000 | $59,883,000 | $19,961,000 | May 05, 2000 |
| 5 | What Women Want (2000) (Paramount) | $314,409,000 | $57,812,000 | $19,271,000 | Dec 15, 2000 |
| 6 | The Perfect Storm (Warner Bros.) | $314,076,000 | $71,076,000 | $23,692,000 | Jun 30, 2000 |
| 7 | Meet the Parents (Universal) | $285,916,000 | $49,226,000 | $16,409,000 | Oct 06, 2000 |
| 8 | X-Men (Fox) | $270,531,000 | $93,684,000 | $31,228,000 | Jul 14, 2000 |
| 9 | Scary Movie (Miramax / Dimension) | $270,050,000 | $72,830,000 | $24,277,000 | Jul 07, 2000 |
| 10 | What Lies Beneath (DreamWorks) | $267,368,000 | $51,086,000 | $17,029,000 | Jul 21, 2000 |
| 11 | Dinosaur (Disney) | $236,907,000 | $66,825,000 | $22,275,000 | May 19, 2000 |
| 12 | Crouching Tiger, Hidden Dragon (Sony Pictures Classics) | $220,276,000 | $1,139,000 | $380,000 | Dec 08, 2000 |
| 13 | Erin Brockovich (Universal) | $216,006,000 | $48,395,000 | $16,132,000 | Mar 17, 2000 |
| 14 | Charlie's Angels (2000) (Sony / Columbia) | $215,506,000 | $69,016,000 | $23,005,000 | Nov 03, 2000 |
| 15 | Traffic (USA Films) | $213,461,000 | $26,690,000 | $8,897,000 | Dec 27, 2000 |
| 16 | Nutty Professor II: The Klumps (Universal) | $212,074,000 | $73,124,000 | $24,375,000 | Jul 28, 2000 |
| 17 | Big Momma's House (Fox) | $202,184,000 | $44,131,000 | $14,710,000 | Jun 02, 2000 |
| 18 | Remember the Titans (Disney) | $198,908,000 | $35,955,000 | $11,985,000 | Sep 29, 2000 |
| 19 | The Patriot (Sony / Columbia) | $194,911,000 | $38,549,000 | $12,850,000 | Jun 28, 2000 |
| 20 | Chicken Run (DreamWorks) | $183,739,000 | $30,108,000 | $10,036,000 | Jun 21, 2000 |
| 21 | Miss Congeniality (Warner Bros.) | $183,692,000 | $23,826,000 | $7,942,000 | Dec 22, 2000 |
| 22 | Gone in 60 Seconds (Disney) | $174,819,000 | $43,573,000 | $14,524,000 | Jun 09, 2000 |
| 23 | Unbreakable (Disney) | $163,405,000 | $52,167,000 | $17,389,000 | Nov 22, 2000 |
| 24 | Me, Myself & Irene (Fox) | $155,767,000 | $41,637,000 | $13,879,000 | Jun 23, 2000 |
| 25 | Space Cowboys (Warner Bros.) | $155,586,000 | $31,119,000 | $10,373,000 | Aug 04, 2000 |
| 26 | The Emperor's New Groove (Disney) | $153,586,000 | $16,876,000 | $5,625,000 | Dec 15, 2000 |
| 27 | Scream 3 (Miramax / Dimension) | $153,314,000 | $59,702,000 | $19,901,000 | Feb 04, 2000 |
| 28 | U-571 (Universal) | $132,639,000 | $33,629,000 | $11,210,000 | Apr 21, 2000 |
| 29 | Rugrats in Paris: The Movie (Paramount) | $131,581,000 | $39,072,000 | $13,024,000 | Nov 17, 2000 |
| 30 | The Family Man (Universal) | $130,353,000 | $25,977,000 | $8,659,000 | Dec 22, 2000 |
| 31 | Hollow Man (Sony / Columbia) | $125,909,000 | $45,429,000 | $15,143,000 | Aug 04, 2000 |
| 32 | Chocolat (2000) (Miramax) | $122,985,000 | $271,000 | $90,000 | Dec 15, 2000 |
| 33 | Shaft (2000) (Paramount) | $120,965,000 | $37,346,000 | $12,449,000 | Jun 16, 2000 |
| 34 | Disney's The Kid (Disney) | $119,860,000 | $21,821,000 | $7,274,000 | Jul 07, 2000 |
| 35 | Vertical Limit (Sony / Columbia) | $119,088,000 | $26,671,000 | $8,890,000 | Dec 08, 2000 |
| 36 | Road Trip (DreamWorks) | $117,879,000 | $26,632,000 | $8,877,000 | May 19, 2000 |
| 37 | Bring It On (Universal) | $117,602,000 | $29,858,000 | $9,953,000 | Aug 25, 2000 |
| 38 | 102 Dalmatians (Disney) | $115,158,000 | $34,199,000 | $11,400,000 | Nov 22, 2000 |
| 39 | Rules of Engagement (Paramount) | $105,488,000 | $25,817,000 | $8,606,000 | Apr 07, 2000 |
| 40 | The Cell (New Line) | $105,486,000 | $30,123,000 | $10,041,000 | Aug 18, 2000 |
| 41 | Mission to Mars (Disney) | $104,710,000 | $39,308,000 | $13,103,000 | Mar 10, 2000 |
| 42 | Coyote Ugly (Disney) | $104,543,000 | $29,787,000 | $9,929,000 | Aug 04, 2000 |
| 43 | Fantasia 2000 (Disney) | $104,319,000 | $3,939,000 | $1,313,000 | Jan 01, 2000 |
| 44 | Snow Day (Paramount) | $103,226,000 | $24,649,000 | $8,216,000 | Feb 11, 2000 |
| 45 | Next Friday (New Line) | $98,597,000 | $24,923,000 | $8,308,000 | Jan 12, 2000 |
| 46 | The Whole Nine Yards (Warner Bros.) | $98,482,000 | $23,617,000 | $7,872,000 | Feb 18, 2000 |
| 47 | Shanghai Noon (Disney) | $97,924,000 | $26,842,000 | $8,947,000 | May 26, 2000 |
| 48 | Romeo Must Die (Warner Bros.) | $96,267,000 | $30,982,000 | $10,327,000 | Mar 22, 2000 |
| 49 | Final Destination (New Line) | $91,723,000 | $17,226,000 | $5,742,000 | Mar 17, 2000 |
| 50 | Finding Forrester (Sony / Columbia) | $89,096,000 | $1,206,000 | $402,000 | Dec 22, 2000 |
| 51 | The Road to El Dorado (DreamWorks) | $87,477,000 | $22,094,000 | $7,365,000 | Mar 31, 2000 |
| 52 | Men of Honor (Fox) | $83,960,000 | $22,942,000 | $7,647,000 | Nov 10, 2000 |
| 53 | Dude, Where's My Car? (Fox) | $80,367,000 | $23,813,000 | $7,938,000 | Dec 15, 2000 |
| 54 | The Tigger Movie (Disney) | $78,346,000 | $16,213,000 | $5,404,000 | Feb 11, 2000 |
| 55 | O Brother, Where Art Thou? (Disney) | $78,276,000 | $336,000 | $112,000 | Dec 22, 2000 |
| 56 | Frequency (New Line) | $77,411,000 | $15,523,000 | $5,174,000 | Apr 28, 2000 |
| 57 | The Replacements (Warner Bros.) | $76,942,000 | $18,986,000 | $6,329,000 | Aug 11, 2000 |
| 58 | Pokemon: The Movie 2000 (Warner Bros.) | $75,258,000 | $33,667,000 | $11,222,000 | Jul 21, 2000 |
| 59 | The Beach (Fox) | $68,425,000 | $26,276,000 | $8,759,000 | Feb 11, 2000 |
| 60 | The Exorcist: The Version You've Never Seen (Warner Bros.) | $68,230,000 | $14,061,000 | $4,687,000 | Sep 22, 2000 |
| 61 | Little Nicky (New Line) | $67,874,000 | $27,628,000 | $9,209,000 | Nov 10, 2000 |
| 62 | Pitch Black (USA Films) | $67,488,000 | $20,009,000 | $6,670,000 | Feb 18, 2000 |
| 63 | The Original Kings of Comedy (Paramount) | $65,668,000 | $19,011,000 | $6,337,000 | Aug 18, 2000 |
| 64 | Bedazzled (2000) (Fox) | $65,160,000 | $22,541,000 | $7,514,000 | Oct 20, 2000 |
| 65 | Autumn in New York (MGM) | $64,944,000 | $18,896,000 | $6,299,000 | Aug 11, 2000 |
| 66 | 28 Days (Sony / Columbia) | $63,927,000 | $17,733,000 | $5,911,000 | Apr 14, 2000 |
| 67 | Keeping the Faith (Disney) | $63,716,000 | $13,894,000 | $4,631,000 | Apr 14, 2000 |
| 68 | Bounce (Miramax) | $63,300,000 | $19,647,000 | $6,549,000 | Nov 17, 2000 |
| 69 | Hanging Up (Sony / Columbia) | $62,001,000 | $27,020,000 | $9,007,000 | Feb 18, 2000 |
| 70 | The Flintstones in Viva Rock Vegas (Universal) | $60,657,000 | $18,090,000 | $6,030,000 | Apr 28, 2000 |
| 71 | The Skulls (Universal) | $60,274,000 | $18,982,000 | $6,327,000 | Mar 31, 2000 |
| 72 | The 6th Day (Sony / Columbia) | $59,514,000 | $22,395,000 | $7,465,000 | Nov 17, 2000 |
| 73 | Thirteen Days (New Line) | $59,494,000 | $16,801,000 | $5,600,000 | Dec 25, 2000 |
| 74 | My Dog Skip (Warner Bros.) | $58,707,000 | $98,000 | $33,000 | Jan 14, 2000 |
| 75 | Where the Heart Is (Fox) | $58,083,000 | $14,263,000 | $4,754,000 | Apr 28, 2000 |
| 76 | Pay It Forward (Warner Bros.) | $57,648,000 | $16,565,000 | $5,522,000 | Oct 20, 2000 |
| 77 | Dracula 2000 (Miramax / Dimension) | $56,793,000 | $14,854,000 | $4,951,000 | Dec 22, 2000 |
| 78 | Return to Me (MGM) | $56,277,000 | $13,451,000 | $4,484,000 | Apr 07, 2000 |
| 79 | Proof of Life (Warner Bros.) | $56,064,000 | $17,556,000 | $5,852,000 | Dec 08, 2000 |
| 80 | Almost Famous (DreamWorks) | $55,955,000 | $3,981,000 | $1,327,000 | Sep 15, 2000 |
| 81 | The Legend of Bagger Vance (DreamWorks) | $53,177,000 | $19,807,000 | $6,602,000 | Nov 03, 2000 |
| 82 | Snatch (Sony / Screen Gems) | $52,160,000 | $48,000 | $16,000 | Dec 08, 2000 |
| 83 | The Art of War (Warner Bros.) | $51,955,000 | $17,905,000 | $5,968,000 | Aug 25, 2000 |
| 84 | Bless the Child (Paramount) | $50,531,000 | $16,190,000 | $5,397,000 | Aug 11, 2000 |
| 85 | The Watcher (Universal) | $49,784,000 | $15,587,000 | $5,196,000 | Sep 08, 2000 |
| 86 | Love & Basketball (New Line) | $47,227,000 | $13,998,000 | $4,666,000 | Apr 21, 2000 |
| 87 | High Fidelity (Disney) | $46,930,000 | $11,057,000 | $3,686,000 | Mar 31, 2000 |
| 88 | Book of Shadows: Blair Witch 2 (Artisan) | $45,468,000 | $22,743,000 | $7,581,000 | Oct 27, 2000 |
| 89 | The Adventures of Rocky & Bullwinkle (Universal) | $44,725,000 | $11,720,000 | $3,907,000 | Jun 30, 2000 |
| 90 | Nurse Betty (USA Films) | $43,290,000 | $12,290,000 | $4,097,000 | Sep 08, 2000 |
| 91 | Reindeer Games (Miramax / Dimension) | $40,191,000 | $13,980,000 | $4,660,000 | Feb 25, 2000 |
| 92 | Titan A.E. (Fox) | $39,133,000 | $16,127,000 | $5,376,000 | Jun 16, 2000 |
| 93 | Billy Elliot (Universal Focus) | $37,828,000 | $371,000 | $124,000 | Oct 13, 2000 |
| 94 | Boys and Girls (Miramax / Dimension) | $37,492,000 | $12,054,000 | $4,018,000 | Jun 16, 2000 |
| 95 | Battlefield Earth (Warner Bros.) | $36,928,000 | $19,862,000 | $6,621,000 | May 12, 2000 |
| 96 | Urban Legends: Final Cut (Sony / Columbia) | $36,923,000 | $14,628,000 | $4,876,000 | Sep 22, 2000 |
| 97 | Down to You (Miramax) | $34,517,000 | $13,075,000 | $4,358,000 | Jan 21, 2000 |
| 98 | Wonder Boys (Paramount) | $33,354,000 | $9,990,000 | $3,330,000 | Feb 23, 2000 |
| 99 | Best in Show (Warner Bros.) | $32,188,000 | $711,000 | $237,000 | Sep 29, 2000 |
| 100 | The Ninth Gate (Artisan) | $32,096,000 | $11,390,000 | $3,797,000 | Mar 10, 2000 |
| 101 | Michael Jordan to the Max (IMAX) | $32,077,000 | $994,000 | $331,000 | May 05, 2000 |
| 102 | The Contender (DreamWorks) | $30,738,000 | $9,225,000 | $3,075,000 | Oct 13, 2000 |
| 103 | Red Planet (Warner Bros.) | $30,065,000 | $14,999,000 | $5,000,000 | Nov 10, 2000 |
| 104 | Small Time Crooks (DreamWorks) | $29,697,000 | $6,675,000 | $2,225,000 | May 19, 2000 |
| 105 | Center Stage (Sony / Columbia) | $29,582,000 | $7,919,000 | $2,640,000 | May 12, 2000 |
| 106 | Boiler Room (New Line) | $29,187,000 | $11,562,000 | $3,854,000 | Feb 18, 2000 |
| 107 | Lost Souls (New Line) | $28,920,000 | $13,681,000 | $4,560,000 | Oct 13, 2000 |
| 108 | Eye of the Beholder (Destination) | $28,379,000 | $10,249,000 | $3,416,000 | Jan 28, 2000 |
| 109 | Thomas and the Magic Railroad (Destination) | $27,404,000 | $7,146,000 | $2,382,000 | Jul 26, 2000 |
| 110 | Cirque du Soleil: Journey of Man (Sony Pictures Classics) | $26,877,000 | $86,000 | $29,000 | May 05, 2000 |
| 111 | Loser (Sony / Columbia) | $26,861,000 | $10,334,000 | $3,445,000 | Jul 21, 2000 |
| 112 | All the Pretty Horses (Miramax) | $26,727,000 | $8,359,000 | $2,786,000 | Dec 25, 2000 |
| 113 | Drowning Mona (Destination) | $26,669,000 | $9,979,000 | $3,326,000 | Mar 03, 2000 |
| 114 | Bait (Warner Bros.) | $26,358,000 | $9,434,000 | $3,145,000 | Sep 15, 2000 |
| 115 | Dungeons & Dragons (2000) (New Line) | $26,178,000 | $12,447,000 | $4,149,000 | Dec 08, 2000 |
| 116 | American Psycho (Lionsgate) | $25,919,000 | $8,532,000 | $2,844,000 | Apr 14, 2000 |
| 117 | The Next Best Thing (Paramount) | $25,781,000 | $10,096,000 | $3,365,000 | Mar 03, 2000 |
| 118 | Get Carter (Warner Bros.) | $25,741,000 | $11,416,000 | $3,805,000 | Oct 06, 2000 |
| 119 | Supernova (MGM) | $24,474,000 | $11,578,000 | $3,859,000 | Jan 14, 2000 |
| 120 | The Ladies Man (Paramount) | $23,418,000 | $9,333,000 | $3,111,000 | Oct 13, 2000 |
| 121 | The Little Vampire (New Line) | $23,343,000 | $9,837,000 | $3,279,000 | Oct 27, 2000 |
| 122 | Dr. T and the Women (Artisan) | $22,554,000 | $8,621,000 | $2,874,000 | Oct 12, 2000 |
| 123 | The Crew (Disney) | $22,398,000 | $6,969,000 | $2,323,000 | Aug 25, 2000 |
| 124 | Highlander: Endgame (Miramax / Dimension) | $22,034,000 | $10,703,000 | $3,568,000 | Sep 01, 2000 |
| 125 | Ready to Rumble (Warner Bros.) | $21,317,000 | $9,043,000 | $3,014,000 | Apr 07, 2000 |
| 126 | Saving Grace (Fine Line) | $20,945,000 | $494,000 | $165,000 | Aug 04, 2000 |
| 127 | The Gift (2000) (Paramount Classics) | $20,653,000 | $20,000 | $7,000 | Dec 22, 2000 |
| 128 | The Legend of Drunken Master (Miramax / Dimension) | $19,874,000 | $6,613,000 | $2,204,000 | Oct 20, 2000 |
| 129 | Cyberworld 3-D (IMAX) | $19,354,000 | $478,000 | $159,000 | Oct 06, 2000 |
| 130 | Here on Earth (Fox) | $18,097,000 | $7,758,000 | $2,586,000 | Mar 15, 2000 |
| 131 | Lucky Numbers (Paramount) | $17,271,000 | $7,802,000 | $2,601,000 | Oct 27, 2000 |
| 132 | Godzilla 2000 (Sony / TriStar) | $17,263,000 | $7,581,000 | $2,527,000 | Aug 18, 2000 |
| 133 | 3 Strikes (MGM) | $16,911,000 | $6,337,000 | $2,112,000 | Mar 03, 2000 |
| 134 | Digimon: The Movie (Fox) | $16,565,000 | $7,281,000 | $2,427,000 | Oct 06, 2000 |
| 135 | You Can Count on Me (Paramount Classics) | $15,794,000 | $203,000 | $68,000 | Nov 10, 2000 |
| 136 | Whatever It Takes (Sony / Columbia) | $15,042,000 | $7,059,000 | $2,353,000 | Mar 24, 2000 |
| 137 | Pollock (Sony Pictures Classics) | $14,787,000 | $76,000 | $25,000 | Dec 15, 2000 |
| 138 | Shadow of the Vampire (Lionsgate) | $14,263,000 | $258,000 | $86,000 | Dec 29, 2000 |
| 139 | Quills (Fox Searchlight) | $12,151,000 | $429,000 | $143,000 | Nov 24, 2000 |
| 140 | Screwed (Universal) | $12,086,000 | $5,745,000 | $1,915,000 | May 12, 2000 |
| 141 | State and Main (Fine Line) | $11,943,000 | $998,000 | $333,000 | Dec 22, 2000 |
| 142 | I Dreamed of Africa (Sony / Columbia) | $11,439,000 | $4,147,000 | $1,382,000 | May 05, 2000 |
| 143 | What Planet Are You From? (Sony / Columbia) | $10,820,000 | $5,175,000 | $1,725,000 | Mar 03, 2000 |
| 144 | Croupier (Shooting Gallery) | $10,666,000 | $109,000 | $36,000 | Apr 21, 2000 |
| 145 | The Way of the Gun (Artisan) | $10,415,000 | $3,699,000 | $1,233,000 | Sep 08, 2000 |
| 146 | Where the Money Is (USA Films) | $9,737,000 | $4,323,000 | $1,441,000 | Apr 14, 2000 |
| 147 | The In Crowd (Warner Bros.) | $9,082,000 | $2,589,000 | $863,000 | Jul 21, 2000 |
| 148 | Black and White (Sony / Columbia) | $9,077,000 | $3,805,000 | $1,268,000 | Apr 07, 2000 |
| 149 | Gossip (Warner Bros.) | $8,786,000 | $3,993,000 | $1,331,000 | Apr 21, 2000 |
| 150 | Woman on Top (Fox Searchlight) | $8,634,000 | $3,454,000 | $1,151,000 | Sep 22, 2000 |
| 151 | The Virgin Suicides (Paramount Classics) | $8,438,000 | $404,000 | $135,000 | Apr 21, 2000 |
| 152 | Duets (Disney) | $8,152,000 | $3,444,000 | $1,148,000 | Sep 15, 2000 |
| 153 | Held Up (Trimark) | $8,093,000 | $3,287,000 | $1,096,000 | May 12, 2000 |
| 154 | The Tao of Steve (Sony Classics) | $7,468,000 | $158,000 | $53,000 | Aug 04, 2000 |
| 155 | Before Night Falls (Fine Line) | $7,296,000 | $147,000 | $49,000 | Dec 22, 2000 |
| 156 | Dancer in the Dark (Fine Line) | $7,198,000 | $158,000 | $53,000 | Sep 22, 2000 |
| 157 | East is East (Miramax) | $7,184,000 | $92,000 | $31,000 | Apr 14, 2000 |
| 158 | Whipped (Destination) | $7,153,000 | $4,695,000 | $1,565,000 | Sep 01, 2000 |
| 159 | Requiem for a Dream (Artisan) | $6,253,000 | $111,000 | $37,000 | Oct 06, 2000 |
| 160 | The Big Blue: Director's Cut (2000) (IDP) | $6,158,000 | $24,000 | $8,000 | Jul 14, 2000 |
| 161 | Malèna (Miramax) | $5,930,000 | $107,000 | $36,000 | Dec 22, 2000 |
| 162 | Price of Glory (New Line) | $5,918,000 | $2,772,000 | $924,000 | Mar 31, 2000 |
| 163 | Ghost Dog: Way of the Samurai (Artisan) | $5,690,000 | $286,000 | $95,000 | Mar 03, 2000 |
| 164 | The Big Kahuna (Lions Gate) | $5,445,000 | $139,000 | $46,000 | Apr 28, 2000 |
| 165 | Beautiful (Destination) | $5,431,000 | $2,424,000 | $808,000 | Sep 29, 2000 |
| 166 | The House of Mirth (Sony Classics) | $5,235,000 | $84,000 | $28,000 | Dec 22, 2000 |
| 167 | Isn't She Great (Universal) | $5,095,000 | $2,352,000 | $784,000 | Jan 28, 2000 |
| 168 | Up at the Villa (USA Films) | $5,045,000 | $584,000 | $195,000 | May 05, 2000 |
